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Promethazine Injection 50mg/2mL
| Specification | 50 mg/2 mL 10's×10/Box |
| Shelf life | 3Years |
| Storage | Store in a cool and dry place below 25ºC, protect from light |
Therapeutic indications
Promethazine Hydrochloride Injection is indicated for the following conditions:
Treatment of allergic reactions such as:
· uncomplicated allergic conditions of the immediate type, e.g., Pruritus, urticaria and angioedema, when oral therapy is impossible or contraindicated;
Treatment and prevention of vomiting including:
· motion sickness;
·drug induced nausea;
·prevention and control of nausea and vomiting associated with certain types of anaesthesia and surgery, such as procedures with a high incidence of postoperative vomiting (e.g., gynaecological surgery, strabismus or middle ear surgery, and electroconvulsive therapy); in patients with a past history of motion sickness or post operative vomiting; and in patients in whom avoidance of vomiting is crucial (e.g., Neurosurgery and eye surgery);
·preoperative, postoperative and obstetric (during labour) sedation.
Dose and method of administration
The preferred route of administration of Promethazine Hydrochloride Injection is by deep intramuscular injection.
Promethazine should only be administered intravenously if the benefits outweigh the risks in an individual patient.
Allergic conditions
Adults: 25 mg - 50 mg by deep intramuscular injection or slow intravenous injection; may be repeated within two hours if necessary. Maximum dose up to 150 mg daily
Antiemetic
Antiemetics should not be used in vomiting of unknown etiology in children and adolescents
In established nausea or vomiting due to causes other than motion sickness:
Adults: 12.5 - 25 mg, by intramuscular or intravenous injection, every four hours as
needed. Children: 5 - 12 yrs old 12.5mg by intramuscular injection.
Sedative/hypnotic
Adults: 25 - 50 mg by intramuscular or intravenous injection.
Children: When oral route is not possible:
2 - 5 yrs old 7.5 - 10 mg by intramuscular injection
6 - 10 yrs old 10 - 12.5 mg by intramuscular injection
Preoperative and postoperative sedation
Adults: 25 - 50 mg by intramuscular or intravenous injection, usually with pethdine
and atropine one hour before surgery.
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