BENZATHINE BENZYLPENICILLIN FOR INJECTION B.P. 2.4 MEGA FOR I.M. USE
This preparation is available in the form of a sterile dry powder containing Benzathine Penicillin with suitable suspending and buffering agents. The advantage of Benzathine Penicillin is that due to their solubility in water very low (about 200IU/ml), so absorption and excretion are slowly, in various Penicillin preparations, Benzathine Penicillin is longest prolonged action. Therefore, a single dose injection of Benzathine Penicillin can maintain an effective concentration in blood for 1-4 weeks. Actions and Uses: It has the same indications as Penicillin. As its peak blood concentrations relatively low, it is only indicated in mild infections caused by Penicillin-sensitive bacteria such as tonsilitis, scarlet fever, erysipelas, furuncles carbuncles. It is also effective for syphilis, Vencent's angina and gonorrhea, rheumatism. Usage and Dosage: It is given by I.M. injection only, A suitable amount water for injection is added into the vial before use, shake well to form a suspension. 600,000IU-1,200,000IU each time once a week. In the case of syphilis 2,400,000IU a time. For prevent of streptococcus infections and control for relapse of rheumatism, 2,400,000IU each time, once 4 weeks. or according to medical order and physician's prescription. Caution: 1. Skin sensitive test of Penicillin should be made before use. It should not be administered to patients hypersensitive to Penicillin. 2. The suspension prepared by adding a suitable amount of water for injection into the vial, should be stored below 10ºC and used up within one week. Packing: 1,200,000IU/vial 2,400,000IU/vial Storage: Store in a cool and dry place below 30ºC, protected from light. Expiry: Three years.
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