Hyoscine Butylbromide Injection 10mg 1ml

• Application: Internal Medicine
• Usage Mode: I.M./I.V.
• Suitable for: Elderly, Children, Adult
• State: Liquid
• Shape: Liquid
• Type: Organic Chemicals
• Model NO.: 10mg 1ml
• Pharmaceutical Technology: Chemical Synthesis
• Transport Package: Carton
• Specification: 10mg/1ml, 10amps, 100amps/box
• Trademark: RYAN PHARMA
• Origin: China

Product Description

Hyoscine Butylbromide Injection
10mg/1ml
COMPOSITION:
It is a sterile solution of Hyoscine Butylbromide in water for injections. Each 1ml of injection contains Hyoscine Butylbromide 10mg.
INDICATIONS AND PHARMACOLOGY:
Hyoscine is a tertiary amine antimuscarinic agent with central and peripheral actions. It is a more powerful suppressant of salivation than atropine, and usually slows rather than increases heart rate, especially in low doses. Its central action differs from that of atropine in that it depresses the cerebral cortex and produces drowsiness and amnesia. Hyoscine butylbromide is quaternary ammonium derivatives.
Hyoscine is effective in the prevention and control of motion sickness and has also been given as an antiemetic in the prophylactic treatment of other forms of nausea. Hyoscine is also given to prevent motion sickness via a transdermal delivery system which is placed behind the ear and supplies 500μg over 3 days.
ADVERSE EFFECTS AND PRECAUTIONS:
In contrast to atropine, hyoscine produces central depression at therapeutic doses and symptoms include drowsiness and fatigue. Toxic doses of hyoscine produce stimulation of the CNS in a similar manner to atropine. However, hyoscine does not stimulate the medullary centers and therefore does not produce the increases in respiration rate or blood pressure seen with atropine. Hyoscine may produce CNS stimulation rather than depression at therapeutic doses if used in the presence of pain without opioid analgesics; symptoms include excitement, restlessness, hallucinations, or delirium.
Hyoscine should not be used concurrently with CNS depressants. Caution has been advised in elderly patients and in patients with impaired metabolic, liver, or kidney function, as adverse CNS effects have been stated to be more likely in these patients. There have been rare reports of an increase in frequency of seizures in epileptic patients. The quaternary derivatives, such as the butylbromide do not readily cross the blood-brain barrier, so central effects are rare.
ADMINISTRATION:
Hyoscine has been given as its quaternary ammonium derivatives in conditions associated with visceral spasm, in usual doses of 10 mg of the butylbromide intramuscularly or intravenously, repeated after 30 minutes if necessary. The use of antimuscarinics in the relief of visceral spasms of the gastro-intestinal tract is discussed on; they may also relieve painful spasms of the biliary and genitourinary systems, although analgesics are normally used.
PRESENTATION:
Ampoule of 1 ml-box of 100 ampoules.
STORAGE:
Store in airtight containers & protect from light.
DOSAGE:
As directed by physician.
KEEP ALL MEDICINES OUT OF THE REACH OF CHILDREN
VALIDITY:
3 years.