Miconazole is used to treat skin infections such as athlete's foot, jock itch, ringworm, and other fungal skin infections (candidiasis). This medication is also used to treat a skin condition known as pityriasis (tinea versicolor), a fungal infection that causes a lightening or darkening of the skin of the neck, chest, arms, or legs. Miconazole is an azole antifungal that works by preventing the growth of fungus. How to use miconazole nitrate topical Use this medication on the skin only. Clean and thoroughly dry the area to be treated. Apply this medication to the affected skin, usually twice a day or as directed by your doctor. If you are using the spray form, shake the bottle well before applying. Dosage and length of treatment depends on the type of infection being treated. Do not apply this more often than prescribed. Your condition will not clear faster, but side effects may be increased. Apply enough medication to cover the affected area and some of the surrounding skin. After applying this medication, wash your hands. Do not wrap, cover or bandage the area unless directed to do so by your doctor. Do not apply this medication in the eyes, nose, mouth, or vagina. Use this medication regularly in order to get the most benefit from it. Remember to use it at the same times each day. Continue to use this medication until the full prescribed amount is finished, even if symptoms disappear after starting miconazole. Stopping the medication too early may allow the fungus to continue to grow, which may result in a relapse of the infection. Inform your doctor if your condition lasts or gets worse.