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For use in the treatment of mild to moderately severe infections caused by penicillin sensitive organisms.
Consideration should be given to official guidance on the appropriate use of antibacterial agents.
Posology
Adults: The dosage is 250-500 mg every six hours.
Elderly: The dosage is as for adults. The dosage should be reduced if renal function is markedly impaired.
Prophylactic Use: The dosage is 250 mg daily for long term prophylaxis of rheumatic fever.
Paediatric population
Children 1-5 years: 125 mg every six hours
6-12 years: 250 mg every six hours
To avoid late complications (rheumatic fever), infections with β-haemolytic streptococci should be treated for 10 days.
The treatment of acute otitis media with penicillin V should be limited to 5 days. However, 5-10 days treatment may be recommended in patients with potential for complications.
Method of administration
Penicillin VK Tablets 250 mg/Phenoxymethylpenicillin 250 mg Film-Coated Tablets are for oral use.
Each tablet should be swallowed whole with water, at least 30 minutes before food, as ingestion of phenoxymethylpenicillin with meals slightly reduces the absorption of the drug.
Phenoxymethylpenicillin is contraindicated in patients with known penicillin hypersensitivity.
Attention should be paid to possible cross-sensitivity with other beta-lactam antibiotics e.g. cephalosporins. Severe acute infections should not be treated with phenoxymethylpenicillin.
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